Genetic diversity and evolution of SARS-CoV-2

被引：400

作者：

Tung Phan ^{[1
,2
]}

机构：

[1] Univ Pittsburgh, Div Clin Microbiol, Pittsburgh, PA 15260 USA

[2] Univ Pittsburgh, Med Ctr, Pittsburgh, PA 15260 USA

来源：

INFECTION GENETICS AND EVOLUTION | 2020年 / 81卷

关键词：

Coronavirus; SARS-CoV-2; Mutations; Genomic diversity;

D O I：

10.1016/j.meegid.2020.104260

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

COVID-19 is a viral respiratory illness caused by a new coronavirus called SARS-CoV-2. The World Health Organization declared the SARS-CoV-2 outbreak a global public health emergency. We performed genetic analyses of eighty-six complete or near-complete genomes of SARS-CoV-2 and revealed many mutations and deletions on coding and non-coding regions. These observations provided evidence of the genetic diversity and rapid evolution of this novel coronavirus.

引用

页数：3

共 11 条

[1] Dhama K, 2020, CLIN MICROBIOL REV, V33, DOI [10.1128/CMR.00028-20, 10.1038/s41432-020-0088-4]
[2] Human Coronavirus: Host-Pathogen Interaction
Fung, To Sing
Liu, Ding Xiang
[J]. ANNUAL REVIEW OF MICROBIOLOGY, VOL 73, 2019, 73 : 529 - 557
[3] Quasispecies Theory and the Behavior of RNA Viruses
Lauring, Adam S.
Andino, Raul
[J]. PLOS PATHOGENS, 2010, 6 (07) : 1 - 8
[4] Novel Coronavirus Pneumonia Outbreak in 2019: Computed Tomographic Findings in Two Cases
Lin, Xiaoqi
Gong, Zhenyu
Xiao, Zuke
Xiong, Jingliang
Fan, Bing
Liu, Jiaqi
[J]. KOREAN JOURNAL OF RADIOLOGY, 2020, 21 (03) : 365 - 368
[5] Initial Cluster of Novel Coronavirus (2019-nCoV) Infections in Wuhan, China Is Consistent with Substantial Human-to-Human Transmission
Nishiura, Hiroshi
Linton, Natalie M.
Akhmetzhanov, Andrei R.
[J]. JOURNAL OF CLINICAL MEDICINE, 2020, 9 (02)
[6] THE NEIGHBOR-JOINING METHOD - A NEW METHOD FOR RECONSTRUCTING PHYLOGENETIC TREES
SAITOU, N
NEI, M
[J]. MOLECULAR BIOLOGY AND EVOLUTION, 1987, 4 (04) : 406 - 425
[7] To KK, 2020, CLIN INFECT DIS
[8] Novel coronavirus: From discovery to clinical diagnostics
Tung Phan
[J]. INFECTION GENETICS AND EVOLUTION, 2020, 79
[9] The COVID-19 epidemic
Velavan, Thirumalaisamy P.
Meyer, Christian G.
[J]. TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2020, 25 (03) : 278 - 280
[10] Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China
Yu, Fei
Du, Lanying
Ojcius, David M.
Pan, Chungen
Jiang, Shibo
[J]. MICROBES AND INFECTION, 2020, 22 (02) : 74 - 79

← 1 2 →