Bioactive peroxides as potential therapeutic agents

被引：151

作者：

Dembitsky, Valery M. ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Sch Pharm, Dept Med Chem & Nat Prod, IL-91120 Jerusalem, Israel

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 2008年 / 43卷 / 02期

关键词：

anticancer; cytotoxic; peroxides; fatty acids; terpenoids; steroids; alkaloids; peptides;

D O I：

10.1016/j.ejmech.2007.04.019

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Present review describes research on more than 280 natural anticancer agents isolated from terrestrial and marine and marine sources and synthetic biologically active peroxides. intensive searches for new classes of pharmacologically potent agents produced by terrestrial organisms have resulted in the discovery of dozens of compounds possessing high cytotoxic, antibacterial, antimalarial, and other activities as an important source of leads for drug discovery. (c) 2007 Elsevier Masson SAS. All rights reserved.

引用

页码：223 / 251

页数：29

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