Anti-inflammatory activity of leaf extract of Verbena officinalis L.

被引:28
作者
Calvo, MI [1 ]
Vilalta, N
San Julián, A
Fernández, M
机构
[1] Univ Lausanne, Ecole Pharm, Inst Pharmacognosie & Phytochim, CH-1015 Lausanne, Switzerland
[2] Univ Navarra, Fac Farm, Dept Farm & Tecnol Farmaceut, E-31080 Pamplona, Spain
关键词
Verbena officinalis; anti-inflammatory activity; verbenalin;
D O I
10.1016/S0944-7113(98)80043-3
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The anti-inflammatory activity of a 50% methanol extract of the leaves of Verbena officinalis L. was investigated on topical and oral administration. In the TPA-induced ear inflammation model the extract showed a high reduction of edema, but in the carrageenin-induced rat paw edema the effect observed was less at the two doses employed. These results confirm the use of this plant in folk medicine as a topical anti-inflammatory, herbal drug.
引用
收藏
页码:465 / 467
页数:3
相关论文
共 5 条
[1]   Identification of the major compounds in extracts of Verbena officinalis L. (Verbenaceae) by HPLC with post-column derivatization [J].
Calvo, MI ;
SanJulian, A ;
Fernandez, M .
CHROMATOGRAPHIA, 1997, 46 (5-6) :241-244
[2]  
FERNANDEZ M, 1981, PLANTAS MED POPULAR, P55
[3]   STRUCTURAL CONSIDERATIONS ON THE IRIDOIDS AS ANTIINFLAMMATORY AGENTS [J].
RECIO, MD ;
GINER, RM ;
MANEZ, S ;
RIOS, JL .
PLANTA MEDICA, 1994, 60 (03) :232-234
[4]   A BIO-ASSAY FOR CONCOMITANT ASSESSMENT OF ANTIPHLOGISTIC AND THYMOLYTIC ACTIVITIES OF TOPICALLY APPLIED CORTICOIDS [J].
TONELLI, G ;
THIBAULT, L ;
RINGLER, I .
ENDOCRINOLOGY, 1965, 77 (04) :625-&
[5]  
WINTER CA, 1962, P SOC EXP BIOL MED, V111, P544