Small molecule macroarray construction via Ugi four-component reactions

被引:52
作者
Lin, Q [1 ]
O'Neill, JC [1 ]
Blackwell, HE [1 ]
机构
[1] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA
关键词
D O I
10.1021/ol051684o
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
We report the construction of small molecule macroarrays via Ugi four-component reactions on planar cellulose supports. Array synthesis was enabled by the development of a high efficiency photocleavable linker system and the strategic use of both water- and microwave-assisted organic reactions.
引用
收藏
页码:4455 / 4458
页数:4
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