Langmuir-Blodgett films of antibodies as mediators of endothelial cell adhesion on polyurethanes

被引：2

作者：

Ahluwalia, A

Basta, G

Ricci, D

Francesconi, R

Domenici, C

Grattarola, M

Palchetti, L

Preininger, C

De Rossi, D

机构：

[1] Univ Pisa, Ctr E Piaggio, I-56126 Pisa, Italy

[2] CNR, Inst Clin Physiol, Pisa, Italy

[3] Univ Genoa, DIBE, I-16145 Genoa, Italy

[4] CNR, IROE, I-50127 Florence, Italy

来源：

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | 1999年 / 10卷 / 03期

关键词：

polyurethane; antibodies; LB film; endothelial cells; adhesion;

D O I：

10.1163/156856299X00360

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The effect of endothelial cell adhesion on polyurethanes coated with Langmuir-Blodgett antibody films has been examined. The films were cross-linked with glutaraldehyde with the aim of providing a densely packed and covalently linked two-dimensional antibody network on the polyurethane surfaces. Our results demonstrate that although,oh neither of the two polyurethanes examined were entirely suited to cellular adhesion, Langmuir-Blodgett antibody films, cross-linked with small concentrations of glutaraldehyde, are more suitable for endothelial cell adhesion than surfaces free of antibody.

引用

页码：295 / 304

页数：10

共 18 条

[1] ANTIGEN RECOGNITION PROPERTIES OF ANTIBODY MONOLAYERS [J].