Modifiying NEMO

被引：24

作者：

Hay, RT ^{[1
]}

机构：

[1] Univ St Andrews, Sch Biol, St Andrews KY16 9ST, Fife, Scotland

来源：

NATURE CELL BIOLOGY | 2004年 / 6卷 / 02期

关键词：

D O I：

10.1038/ncb0204-89

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Genotoxic stress induces a survival response by releasing the transcription factor NF-kappaB from its inhibitor IkappaBalpha. In response to DNA damage, this initially requires the nuclear modification of the IkappaB kinase regulator NEMO/IKKgamma. by SUMO and ubiquitin.

引用

页码：89 / 91

页数：4

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