Asymmetric hetero Diels-Alder route to quaternary carbon centers: synthesis of (-)-malyngolide

被引：31

作者：

Ghosh, AK ^{[1
]}

Shirai, M ^{[1
]}

机构：

[1] Univ Illinois, Dept Chem, Chicago, IL 60607 USA

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 36期

关键词：

D O I：

10.1016/S0040-4039(01)01227-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conformationally constrained chiral bis(oxazoline)-metal complex catalyzed asymmetric hetero Diels Alder reactions of Danishefsky's diene and a variety of alpha -keto esters constructed quaternary carbon centers enantio selectively. The reaction was utilized in the synthesis of (-)-malyngolide. (C) 2001 Elsevier Science Ltd. All rights reserved.

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页码：6231 / 6233

页数：3

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