5-chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfonamide (SB-271046):: A potent, selective, and orally bioavailable 5-HT6 receptor antagonist

被引：174

作者：

Bromidge, SM

Brown, AM

Clarke, SE

Dodgson, K

Gager, T

Grassam, HL

Jeffrey, PM

Joiner, GF

King, FD

Middlemiss, DN

Moss, SF

Newman, H

Riley, G

Routledge, C

Wyman, P

机构：

[1] SmithKline Beecham Pharmaceut, Dept Med Chem, Discovery Res, Harlow CM19 5AW, Essex, England

[2] SmithKline Beecham Pharmaceut, Dept Neurosci Res, Discovery Res, Harlow CM19 5AW, Essex, England

[3] SmithKline Beecham Pharmaceut, Dept Drug Metab & Pharmacokinet, Discovery Res, Harlow CM19 5AW, Essex, England

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1999年 / 42卷 / 02期

关键词：

D O I：

10.1021/jm980532e

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：202 / 205

页数：4

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