Blood Vessel Deformations on Microsecond Time Scales by Ultrasonic Cavitation

被引：256

作者：

Chen, Hong ^{[1
]}

Kreider, Wayne ^{[1
]}

Brayman, Andrew A. ^{[1
]}

Bailey, Michael R. ^{[1
]}

Matula, Thomas J. ^{[1
]}

机构：

[1] Univ Washington, Appl Phys Lab, Ctr Ind & Med Ultrasound, Seattle, WA 98105 USA

来源：

PHYSICAL REVIEW LETTERS | 2011年 / 106卷 / 03期

关键词：

CONTRAST AGENTS; BUBBLES; MICROBUBBLES; BOUNDARIES; EXPANSION; DELIVERY; DYNAMICS; GENE; TUBE; WALL;

D O I：

10.1103/PhysRevLett.106.034301

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Transient interactions among ultrasound, microbubbles, and microvessels were studied using high-speed photomicrography. We observed liquid jets, vessel distention (motion outward against the surrounding tissue), and vessel invagination (motion inward toward the lumen). Contrary to current paradigms, liquid jets were directed away from the nearest vessel wall and invagination exceeded distention. These observations provide insight into the mechanics of bubble-vessel interactions, which appear to depend qualitatively upon the mechanical properties of biological tissues.

引用

页数：4

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