Asymmetric transfer hydrogenation of ketones with a polyethylene glycol bound Ru catalyst in water

被引：46

作者：

Liu, Juntao ^{[1
]}

Zhou, Yougui ^{[1
]}

Wu, Yinuo ^{[1
]}

Li, Xingshu ^{[1
]}

Chan, Albert S. C. ^{[1
,2
,3
]}

机构：

[1] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Peoples R China

[2] Hong Kong Polytech Univ, Open Lab Chirotechnol, Inst Mol Technol Drug Discovery & Synth, Hong Kong, Hong Kong, Peoples R China

[3] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2008年 / 19卷 / 07期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/j.tetasy.2008.03.015

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A new polyethylene glycol supported Ru catalyst was synthesized and applied in the asymmetric transfer hydrogenation of various aromatic ketones in water with high chemical yields and enantioselectivities without adding any surfactants. The catalyst could be easily recycled several times without a significant loss of enantioselectivity and activity. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：832 / 837

页数：6

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