An ecosystem of cancer cell line factories to support a cancer dependency map

被引：56

作者：

Boehm, Jesse S. ^{[1
]}

Golub, Todd R. ^{[1
,2
,3
,4
]}

机构：

[1] Broad Inst Harvard & MIT, Cambridge, MA 02142 USA

[2] Dana Farber Canc Inst, Boston, MA 02215 USA

[3] Harvard Univ, Sch Med, Boston, MA 02115 USA

[4] Howard Hughes Med Inst, Chevy Chase, MD 20815 USA

来源：

NATURE REVIEWS GENETICS | 2015年 / 16卷 / 07期

关键词：

DRUG-SENSITIVITY;

D O I：

10.1038/nrg3967

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Jesse Boehm and Todd Golub call for an international effort to establish >10,000 cancer cell line models as a community resource. Cancer cell line factories will facilitate the creation of a cancer dependency map, connecting cancer genomics to therapeutic dependencies.

引用

页码：373 / 374

页数：2

共 5 条

[1] The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity [J].

Barretina, Jordi ;

Caponigro, Giordano ;

Stransky, Nicolas ;

Venkatesan, Kavitha ;

Margolin, Adam A. ;

Kim, Sungjoon ;

Wilson, Christopher J. ;

Lehar, Joseph ;

Kryukov, Gregory V. ;

Sonkin, Dmitriy ;

Reddy, Anupama ;

Liu, Manway ;

Murray, Lauren ;

Berger, Michael F. ;

Monahan, John E. ;

Morais, Paula ;

Meltzer, Jodi ;

Korejwa, Adam ;

Jane-Valbuena, Judit ;

Mapa, Felipa A. ;

Thibault, Joseph ;

Bric-Furlong, Eva ;

Raman, Pichai ;

Shipway, Aaron ;

Engels, Ingo H. ;

Cheng, Jill ;

Yu, Guoying K. ;

Yu, Jianjun ;

Aspesi, Peter, Jr. ;

de Silva, Melanie ;

Jagtap, Kalpana ;

Jones, Michael D. ;

Wang, Li ;

Hatton, Charles ;

Palescandolo, Emanuele ;

Gupta, Supriya ;

Mahan, Scott ;

Sougnez, Carrie ;

Onofrio, Robert C. ;

Liefeld, Ted ;

MacConaill, Laura ;

Winckler, Wendy ;

Reich, Michael ;

Li, Nanxin ;

Mesirov, Jill P. ;

Gabriel, Stacey B. ;

Getz, Gad ;

Ardlie, Kristin ;

Chan, Vivien ;

Myer, Vic E. .

NATURE, 2012, 483 (7391) :603-607

[2] Systematic identification of genomic markers of drug sensitivity in cancer cells [J].

Garnett, Mathew J. ;

Edelman, Elena J. ;

Heidorn, Sonja J. ;

Greenman, Chris D. ;

Dastur, Anahita ;

Lau, King Wai ;

Greninger, Patricia ;

Thompson, I. Richard ;

Luo, Xi ;

Soares, Jorge ;

Liu, Qingsong ;

Iorio, Francesco ;

Surdez, Didier ;

Chen, Li ;

Milano, Randy J. ;

Bignell, Graham R. ;

Tam, Ah T. ;

Davies, Helen ;

Stevenson, Jesse A. ;

Barthorpe, Syd ;

Lutz, Stephen R. ;

Kogera, Fiona ;

Lawrence, Karl ;

McLaren-Douglas, Anne ;

Mitropoulos, Xeni ;

Mironenko, Tatiana ;

Thi, Helen ;

Richardson, Laura ;

Zhou, Wenjun ;

Jewitt, Frances ;

Zhang, Tinghu ;

O'Brien, Patrick ;

Boisvert, Jessica L. ;

Price, Stacey ;

Hur, Wooyoung ;

Yang, Wanjuan ;

Deng, Xianming ;

Butler, Adam ;

Choi, Hwan Geun ;

Chang, JaeWon ;

Baselga, Jose ;

Stamenkovic, Ivan ;

Engelman, Jeffrey A. ;

Sharma, Sreenath V. ;

Delattre, Olivier ;

Saez-Rodriguez, Julio ;

Gray, Nathanael S. ;

Settleman, Jeffrey ;

Futreal, P. Andrew ;

Haber, Daniel A. .

NATURE, 2012, 483 (7391) :570-U87

[3] Discovery and saturation analysis of cancer genes across 21 tumour types [J].

Lawrence, Michael S. ;

Stojanov, Petar ;

Mermel, Craig H. ;

Robinson, James T. ;

Garraway, Levi A. ;

Golub, Todd R. ;

Meyerson, Matthew ;

Gabriel, Stacey B. ;

Lander, Eric S. ;

Getz, Gad .

NATURE, 2014, 505 (7484) :495-+

[4] ROCK Inhibitor and Feeder Cells Induce the Conditional Reprogramming of Epithelial Cells [J].

Liu, Xuefeng ;

Ory, Virginie ;

Chapman, Sandra ;

Yuan, Hang ;

Albanese, Chris ;

Kallakury, Bhaskar ;

Timofeeva, Olga A. ;

Nealon, Caitlin ;

Dakic, Aleksandra ;

Simic, Vera ;

Haddad, Bassem R. ;

Rhim, Johng S. ;

Dritschilo, Anatoly ;

Riegel, Anna ;

McBride, Alison ;

Schlegel, Richard .

AMERICAN JOURNAL OF PATHOLOGY, 2012, 180 (02) :599-607

[5] Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients [J].

van de Wetering, Marc ;

Francies, Hayley E. ;

Francis, Joshua M. ;

Bounova, Gergana ;

Iorio, Francesco ;

Pronk, Apollo ;

van Houdt, Winan ;

van Gorp, Joost ;

Taylor-Weiner, Amaro ;

Kester, Lennart ;

McLaren-Douglas, Anne ;

Blokker, Joyce ;

Jaksani, Sridevi ;

Bartfeld, Sina ;

Volckman, Richard ;

van Sluis, Peter ;

Li, Vivian S. W. ;

Seepo, Sara ;

Pedamallu, Chandra Sekhar ;

Cibulskis, Kristian ;

Carter, Scott L. ;

McKenna, Aaron ;

Lawrence, Michael S. ;

Lichtenstein, Lee ;

Stewart, Chip ;

Koster, Jan ;

Versteeg, Rogier ;

van Oudenaarden, Alexander ;

Saez-Rodriguez, Julio ;

Vries, Robert G. J. ;

Getz, Gad ;

Wessels, Lodewyk ;

Stratton, Michael R. ;

McDermott, Ultan ;

Meyerson, Matthew ;

Garnett, Mathew J. ;

Clevers, Hans .

CELL, 2015, 161 (04) :933-945

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