R We There Yet? R-Loop Hazards to Finishing the Journey

被引：6

作者：

Potenski, Catherine J. ^{[1
]}

Klein, Hannah L. ^{[1
]}

机构：

[1] NYU, Sch Med, Dept Biochem, New York, NY 10016 USA

来源：

MOLECULAR CELL | 2011年 / 44卷 / 06期

关键词：

TRANSCRIPTION; INSTABILITY; ELONGATION; COMPLEX;

D O I：

10.1016/j.molcel.2011.12.003

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA:DNA hybrids in the genome are constantly being generated as a by-product of transcription; in this issue, two papers, from Helmrich et al. (2011) and Wahba et al. (2011), provide insight into how RNA:DNA hybrids lead to genetic instability.

引用

页码：848 / 850

页数：3

共 11 条

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