Vertebrate LTR retrotransposons of the Tf1/Sushi group

被引：45

作者：

Butler, M ^{[1
]}

Goodwin, T ^{[1
]}

Simpson, M ^{[1
]}

Singh, M ^{[1
]}

Poulter, R ^{[1
]}

机构：

[1] Univ Otago, Dept Biochem, Dunedin, New Zealand

来源：

JOURNAL OF MOLECULAR EVOLUTION | 2001年 / 52卷 / 03期

关键词：

vertebrate LTR retrotransposon; programmed phase shifting; reverse transcriptase self-priming; mammalian retrotransposon;

D O I：

10.1007/s002390010154

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

LTR retrotransposons of the Tf1/sushi group from a diversity of vertebrates, including fish, amphibians, and mammals (humans, mice, and others), are described as full-length or partial elements. These elements are compared, and the mechanisms involved in self-priming of reverse transcriptase and programmed phase shifting are inferred. Evidence is presented that in mammals these elements are still transcriptionally active and are represented as proteins. This suggests that members of the Tf1/sushi group are present as functional elements (or incorporated as partial elements into host genes)in diverse vertebrate lineages.

引用

页码：260 / 274

页数：15

共 57 条

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