Approaches to the solid phase of a cyclotriveratrylene scaffold-based tripodal library as potential artificial receptors

被引：19

作者：

Chamorro, C ^{[1
]}

Liskamp, RMJ ^{[1
]}

机构：

[1] Univ Utrecht, Utrecht Inst Pharmaceut Sci, Dept Med Chem, NL-3508 TB Utrecht, Netherlands

来源：

JOURNAL OF COMBINATORIAL CHEMISTRY | 2003年 / 5卷 / 06期

关键词：

D O I：

10.1021/cc034003u

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two versatile tripodal cyclotriveratrylene (CTV)-based scaffolds (7 and 9) have been prepared for the solid phase construction of libraries of tripodal artificial synthetic receptors. A 2197-member library of CTV-based tripodal receptor molecules, 20{1-13,1-13,1-13}, was prepared on the solid phase using split-mix synthesis. The CTV-based receptors contain three peptide arms; one of them is attached to the solid phase and is different from the other two identical peptide arms.

引用

页码：794 / 801

页数：8