FLT3 mutations in childhood acute lymphoblastic leukemia at first relapse

被引:10
作者
Wellmann, S [1 ]
Moderegger, E [1 ]
Zelmer, A [1 ]
Bettkober, M [1 ]
von Stackelberg, A [1 ]
Henze, G [1 ]
Seeger, K [1 ]
机构
[1] Med Univ Berlin, Charite, Dept Pediat Oncol & Hematol, D-13353 Berlin, Germany
关键词
D O I
10.1038/sj.leu.2403655
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:467 / 468
页数:2
相关论文
共 8 条
[1]   FLT3 mutations in childhood acute lymphoblastic leukemia [J].
Armstrong, SA ;
Mabon, ME ;
Silverman, LB ;
Li, AH ;
Gribben, JG ;
Fox, EA ;
Sallan, SE ;
Korsmeyer, SJ .
BLOOD, 2004, 103 (09) :3544-3546
[2]  
BROWN P, 2004, BLOOD 0916
[3]  
HENZE G, 1991, BLOOD, V78, P1166
[4]   FLT3: ITDoes matter in leukemia [J].
Levis, M ;
Small, D .
LEUKEMIA, 2003, 17 (09) :1738-1752
[5]   The role of FLT3 in haematopoietic malignancies [J].
Stirewalt, DL ;
Radich, JP .
NATURE REVIEWS CANCER, 2003, 3 (09) :650-U1
[6]   FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy [J].
Taketani, T ;
Taki, T ;
Sugita, K ;
Furuichi, Y ;
Ishii, E ;
Hanada, R ;
Tsuchicla, M ;
Sugita, K ;
Ida, K ;
Hayashi, Y .
BLOOD, 2004, 103 (03) :1085-1088
[7]   Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia:: association with FAB subtypes and identification of subgroups with poor prognosis [J].
Thiede, C ;
Steudel, C ;
Mohr, B ;
Schaich, M ;
Schäkel, U ;
Platzbecker, U ;
Wermke, M ;
Bornhäuser, M ;
Ritter, M ;
Neubauer, A ;
Ehninger, G ;
Illmer, T .
BLOOD, 2002, 99 (12) :4326-4335
[8]   FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells [J].
Zheng, R ;
Levis, M ;
Piloto, O ;
Brown, P ;
Baldwin, BR ;
Gorin, NC ;
Beran, M ;
Zhu, ZP ;
Ludwig, D ;
Hicklin, D ;
Witte, L ;
Li, YW ;
Small, D .
BLOOD, 2004, 103 (01) :267-274