Intermolecular hydrogen binding of a chiral host and a prochiral imidazolidinone:: enantioselective Norrish-Yang cyclisation in solution

被引:27
作者
Bach, T
Aechtner, T
Neumüller, B [1 ]
机构
[1] Tech Univ Munich, Lehrstuhl Organ Chem 1, D-85747 Garching, Germany
[2] Univ Marburg, Fachbereich Chem, D-35032 Marburg, Germany
关键词
D O I
10.1039/b100300n
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The Norrish-Yang cyclisation of a prochiral imidazolidinone which was conducted in the presence of a chiral host afforded enantiomerically enriched (up to 26% ee) 1,3-diazabicyclo[3.3.0]octanones in good yields (73-86%) with a distinct preference for the exo-diastereoisomer (dr = 77/23-90/10).
引用
收藏
页码:607 / 608
页数:2
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