Photo-pH dually modulated fluorescence switch based on DNA spatial nanodevice

被引：45

作者：

Liu, Huajie ^{[1
]}

Zhou, Yucheng ^{[2
]}

Yang, Yang ^{[1
]}

Wang, Wenxing ^{[1
]}

Qu, Li ^{[2
]}

Chen, Chen ^{[1
]}

Liu, Dongsheng ^{[1
]}

Zhang, Deqing ^{[2
]}

Zhu, Daoben ^{[2
]}

机构：

[1] Natl Ctr Nanosci & Technol, Beijing 100080, Peoples R China

[2] Chinese Acad Sci, Inst Chem, Beijing 100080, Peoples R China

来源：

JOURNAL OF PHYSICAL CHEMISTRY B | 2008年 / 112卷 / 22期

关键词：

D O I：

10.1021/jp8020485

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

In this paper, we describe our strategy on the design, construction, and characterization of a novel molecular device. By integrating a photoregulated fluorescent switch and a DNA-based nanomachine, the distance-dependent FRET process between fluorescein and photochromic moieties can be further modulated by the spatial output of a unique proton-driven DNA manomachine. This device Could be reversibly switched in a reliable manner, and the fluorescence variation behavior, exhibited by this dually modulated fluorescence switch, can also mimic the function of a Boolean logic operation.

引用

页码：6893 / 6896

页数：4

共 32 条

[1] DNA duplex-quadruplex exchange as the basis for a nanomolecular machine [J].

Alberti, P ;

Mergny, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (04) :1569-1573

[2] Molecular logic circuits [J].

Balzani, V ;

Credi, A ;

Venturi, M .

CHEMPHYSCHEM, 2003, 4 (01) :49-59

[3] Spiropyrans and spirooxazines for memories and switches [J].

Berkovic, G ;

Krongauz, V ;

Weiss, V .

CHEMICAL REVIEWS, 2000, 100 (05) :1741-1753

[4]

Berova N., 2000, CIRCULAR DICHROISM P, P337

[5] Construction of molecular logic gates with a DNA-cleaving deoxyribozyme [J].

Chen, X ;

Wang, YF ;

Liu, Q ;

Zhang, ZZ ;

Fan, CH ;

He, L .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (11) :1759-1762

[6] Molecular-scale logic gates [J].

de Silva, AP ;

McClenaghan, ND .

CHEMISTRY-A EUROPEAN JOURNAL, 2004, 10 (03) :574-586

[7]

Feringa B.L., 2001, Molecular Switches

[8] A TETRAMERIC DNA-STRUCTURE WITH PROTONATED CYTOSINE.CYTOSINE BASE-PAIRS [J].

GEHRING, K ;

LEROY, JL ;

GUERON, M .

NATURE, 1993, 363 (6429) :561-565

[9] Synthesis and spectral investigations of a new dyad with spiropyran and fluorescein units: Toward information processing at the single molecular level [J].

Guo, XF ;

Zhang, XF ;

Zhang, DQ ;

Zhou, YC ;

Zhu, DB .

JOURNAL OF ORGANIC CHEMISTRY, 2003, 68 (14) :5681-5687

[10] Molecular switches controlled by light [J].

Gust, D ;

Moore, TA ;

Moore, AL .

CHEMICAL COMMUNICATIONS, 2006, (11) :1169-1178

← 1 2 3 4 →