Outcomes of older people admitted to postacute facilities with delirium

被引:191
作者
Marcantonio, ER
Kiely, DK
Simon, SE
Orav, EJ
Jones, RN
Murphy, KM
Bergmann, MA
机构
[1] Beth Israel Deaconess Med Ctr, Div Gen Med & Primary Care, Boston, MA 02215 USA
[2] Hebrew Senior Life, Res & Training Inst, Boston, MA USA
[3] Brigham & Womens Hosp, Div Gen Med, Boston, MA 02115 USA
[4] Harvard Univ, Sch Med, Div Aging, Boston, MA 02115 USA
关键词
delirium; outcomes; postacute care; rehabilitation;
D O I
10.1111/j.1532-5415.2005.53305.x
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
OBJECTIVES: To compare outcomes of patients admitted to postacute skilled nursing facilities with delirium, subsyndromal delirium, and no delirium. DESIGN: Observational cohort study. SETTING: Seven skilled nursing facilities that specialize in postacute care within a single metropolitan region. PARTICIPANTS: Five hundred four subjects chosen from 1,248 consenting subjects aged 65 and older who underwent mental status testing within 5 days of admission to the participating facilities. Subjects who met full Confusion Assessment Method (CAM) criteria were classified as delirious, those with one or more CAM criteria were classified as having subsyndromal delirium, and those with no CAM features were classified as having no delirium. All subjects with delirium and with available medical records were included. A random subset of subjects with no delirium and subsyndromal delirium with available medical records was included. MEASUREMENTS: The medical records of all subjects underwent a structured review by trained research nurses who were masked to the subjects' initial delirium status. Records were reviewed for the development of new complications within the postacute setting and to determine whether the subjects were discharged within 30 days and, if so, the discharge destination. The National Death Index was used to assess 6-month mortality. RESULTS: Subjects with delirium were more likely to experience one or more complications than subjects with no delirium (73% vs 41%, P < .01). Within 30 days of postacute admission, subjects with delirium were more than twice as likely to be rehospitalized (30% vs 13%), and less than half as likely to be discharged to the community (30% vs 73%) than subjects without delirium (differences P < .01). Subjects with subsyndromal delirium had outcomes intermediate between those with and without delirium. Finally, subjects admitted to the postacute setting with delirium experienced a 6-month mortality rate of 25.0%, compared with 5.7% in subjects admitted without delirium. Subjects with subsyndromal delirium had a 6-month mortality rate of 18.3%. CONCLUSION: Patients admitted to postacute skilled nursing facilities with delirium are more likely to experience complications, rehospitalization, and death than patients without delirium. These findings support the need for improved case finding and management of delirium in postacute care.
引用
收藏
页码:963 / 969
页数:7
相关论文
共 38 条
[31]   Delirium is independently associated with poor functional recovery after hip fracture [J].
Marcantonio, ER ;
Flacker, JM ;
Michaels, M ;
Resnick, NM .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2000, 48 (06) :618-624
[32]   Distribution of macrolide resistance genes erm(B) and mef(A) among 160 penicillin-intermediate clinical isolates of Streptococcus pneumoniae isolated in Southern France [J].
Marchandin, H ;
Jean-Pierre, H ;
Jumas-Bilak, E ;
Isson, L ;
Drouillard, B ;
Darbas, H ;
Carrière, C .
PATHOLOGIE BIOLOGIE, 2001, 49 (07) :522-527
[33]   Diagnostic and Statistical Manual of Mental Disorders [J].
Mittal, Vijay A. ;
Walker, Elaine F. .
PSYCHIATRY RESEARCH, 2011, 189 (01) :158-159
[34]   ACUTE DELIRIUM AND FUNCTIONAL DECLINE IN THE HOSPITALIZED ELDERLY PATIENT [J].
MURRAY, AM ;
LEVKOFF, SE ;
WETLE, TT ;
BECKETT, L ;
CLEARY, PD ;
SCHOR, JD ;
LIPSITZ, LA ;
ROWE, JW ;
EVANS, DA .
JOURNALS OF GERONTOLOGY, 1993, 48 (05) :M181-M186
[35]   The prognostic significance of delirium in older hospital patients [J].
OKeeffe, S ;
Lavan, J .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1997, 45 (02) :174-178
[36]   ADAPTING A CLINICAL COMORBIDITY INDEX FOR USE WITH ICD-9-CM ADMINISTRATIVE DATA - DIFFERING PERSPECTIVES [J].
ROMANO, PS ;
ROOS, LL ;
JOLLIS, JG .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 1993, 46 (10) :1075-1079
[37]   The "Subsyndromal" syndromes of aging [J].
Royall, DR .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2004, 52 (03) :463-465
[38]  
Simon SE, 2001, GERONTOLOGIST, V41, P365