GenoProfiler: batch processing of high-throughput capillary fingerprinting data

被引:34
作者
You, Frank M.
Luo, Ming-Cheng
Gu, Yong Qiang
Lazo, Gerard R.
Deal, Karin
Dvorak, Jan
Anderson, Olin D.
机构
[1] USDA ARS, Western Reg Res Ctr, Albany, CA 94710 USA
[2] Univ Calif Davis, Dept Plant Sci, Davis, CA 95616 USA
基金
美国国家科学基金会;
关键词
D O I
10.1093/bioinformatics/btl494
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
High-throughput content fingerprinting techniques employing capillary electrophoresis place new demands on the editing of fingerprint files for the downstream contig assembly program, FPC. A cross-platform software application, GenoProfiler, was developed for automated editing of sized fingerprinting profiles generated by the ABI Genetic Analyzers. The batch-processing module extracts the sized fragment information directly from the ABI raw trace files, or from data files exported from GeneMapper or other size calling software, removes the background noise and undesired fragments, and generates fragment size files compatible with the FPC software.
引用
收藏
页码:240 / 242
页数:3
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