Separation of inosine, hypoxanthine, and guanosine by high-performance liquid chromatography on silica

被引：8

作者：

Kazoka, H ^{[1
]}

机构：

[1] Latvian Inst Organ Synth, LV-1006 Riga, Latvia

来源：

JOURNAL OF CHROMATOGRAPHIC SCIENCE | 2001年 / 39卷 / 07期

关键词：

D O I：

10.1093/chromsci/39.7.265

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The separation of inosine (Ino), hypoxanthine (Hyp), and guanosine (Guo) on silica has been studied. In adsorption normal-phase systems the peak shapes are unsatisfactory; a low selectivity has been observed for the Ino-Hyp and Guo-Hyp pairs. Chromatograms can be significantly improved if systems with a mixed partition-adsorption retention mechanism are applied.

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页码：265 / 268

页数：4

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