Cellular and molecular facets of keratinocyte reepithelization during wound healing

被引：296

作者：

Santoro, MM ^{[1
]}

Gaudino, G ^{[1
]}

机构：

[1] Univ Piemonte Orientale, Dept Med Sci, I-28100 Novara, Italy

来源：

EXPERIMENTAL CELL RESEARCH | 2005年 / 304卷 / 01期

关键词：

keratinocyte; wound healing; reepithelization;

D O I：

10.1016/j.yexcr.2004.10.033

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cutaneous wound healing is a highly coordinated physiological process that rapidly and efficiently restores skin integrity. Reepithelization is a crucial step during wound healing, which involves migration and proliferation of keratinocytes to cover the denuded dermal surface. Recent advances in wound biology clarified the molecular pathways governing keratinocyte reepithelization at wound sites. These new findings point towards novel therapeutic targets and provide suitable methods to promote faster tissue regeneration in vivo. (C) 2004 Elsevier Inc. All rights reserved.

引用

页码：274 / 286

页数：13

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