Usefulness of a narrow-band reflectance spectrophotometer in evaluating effects of depigmenting treatment

被引:40
作者
Yoshimura, K [1 ]
Harii, K [1 ]
Masuda, Y [1 ]
Takahashi, M [1 ]
Aoyama, T [1 ]
Iga, T [1 ]
机构
[1] Univ Tokyo, Dept Plast & Reconstruct Surg, Bunkyo Ku, Tokyo 1138655, Japan
关键词
depigmenting treatment; retinoic acid aqueous gel; senile lentigines; nevus spilus;
D O I
10.1007/s002660010109
中图分类号
R61 [外科手术学];
学科分类号
摘要
As a depigmenting treatment, combined topical applications of all-trans retinoic acid (atRA) aqueous gel and 5% hydroquinone, 7% lactic acid ointment were used for Oriental patients with hyperpigmented skin lesions such as senile lentigines and nevus spilus. A narrow-band reflectance spectrophotometer and a tristimulus colorimeter were used to evaluate objectively the intensity of pigmentation and erythema at each clinical visit. L*, a*, and b* values measured with a tristimulus colorimeter (Chroma Meter CR-300) enabled the evaluation of erythema but not pigmentation. On the other hand, the melanin and hemoglobin values measured with a narrow-band reflectance spectrophotometer (Mexameter MX-16) expressed both erythema and pigmentation well. It was revealed that, in our bleaching protocol, the narrow-band reflectance spectrophotometer was quite useful for estimating accurately the intensity of pigmentation and erythema and determining the best time point for the cessation of atRA treatment.
引用
收藏
页码:129 / 133
页数:5
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