Versatile synthesis of myo-inositol phospholipid precursors

被引:9
作者
Grove, SJA
Gilbert, IH
Holmes, AB
Painter, GF
Hill, ML
机构
[1] UNIV CAMBRIDGE, CAMBRIDGE CTR MOL RECOGNIT, DEPT CHEM, CAMBRIDGE CB2 1EW, ENGLAND
[2] UNIV CAMBRIDGE, DEPT CHEM, MELVILLE LAB POLYMER SYNTH, CAMBRIDGE CB2 3RA, ENGLAND
[3] GLAXO WELLCOME RES & DEV LTD, MED RES CTR, STEVENAGE SG1 2NY, HERTS, ENGLAND
关键词
D O I
10.1039/a703044d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Homochiral myo-inositol derivatives 16 and 20 and their corresponding enantiomers possessing either the natural or unnatural ring stereochemistry for inositol phospholipids are synthesised from myo-inositol derivatives 8 and 9 respectively using camphor dimethyl acetals in a resolution-protection sequence.
引用
收藏
页码:1633 / 1634
页数:2
相关论文
共 21 条
[21]   SYNTHESIS OF 1D-DISTEAROYLPHOSPHATIDYL-MYO-INOSITOL 3,4,5-TRIS(DIHYDROGEN PHOSPHATE) [J].
WATANABE, Y ;
TOMIOKA, M ;
OZAKI, S .
TETRAHEDRON, 1995, 51 (33) :8969-8976