CD4+CD25+-regulatory T cells from mouse to man

被引：64

作者：

Wing, K

Suri-Payer, E

Rudin, A

机构：

[1] Univ Gothenburg, Sahlgrenska Acad, Dept Rheumatol & Inflammat Res, SE-41346 Gothenburg, Sweden

[2] German Canc Res Ctr, Div Immunogenet, D-6900 Heidelberg, Germany

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 2005年 / 62卷 / 01期

关键词：

D O I：

10.1111/j.1365-3083.2005.01634.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immunological tolerance is one of the fundamental concepts of the immune system. During the past decade, CD4(+)CD25(+)-regulatory T cells have emerged as key players in the development of tolerance to autoantigens as well as to foreign antigens. Still many questions remain illusive regarding the basic properties of CD4(+)CD25(+)-regulatory T cells. This review aims to recapitulate some of the current understandings about the phenotype, function and clinical relevance of murine and human CD4(+)CD25(+)-regulatory T cells.

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页码：1 / 15

页数：15

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