From gene expression to disease risk

被引:57
作者
Dermitzakis, Emmanouil T. [1 ]
机构
[1] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England
关键词
D O I
10.1038/ng0508-492
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Gene expression can be an indicator of cellular state, and studies characterizing variation in gene expression have been useful on the cellular level. Two new studies now provide the first direct demonstration of the successful use of the multidimensionality of gene expression to dissect the genetic architecture of complex diseases.
引用
收藏
页码:492 / 493
页数:3
相关论文
共 11 条
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Stranger, Barbara E. ;
Forrest, Matthew S. ;
Dunning, Mark ;
Ingle, Catherine E. ;
Beazley, Claude ;
Thorne, Natalie ;
Redon, Richard ;
Bird, Christine P. ;
de Grassi, Anna ;
Lee, Charles ;
Tyler-Smith, Chris ;
Carter, Nigel ;
Scherer, Stephen W. ;
Tavare, Simon ;
Deloukas, Panagiotis ;
Hurles, Matthew E. ;
Dermitzakis, Emmanouil T. .
SCIENCE, 2007, 315 (5813) :848-853