Non-invasive and remote detection of cataracts during space exploration with dynamic light scattering

被引:2
作者
Ansari, RR [1 ]
Giblin, F [1 ]
King, JF [1 ]
Lambert, LM [1 ]
机构
[1] NASA Glenn Res Ctr, Natl Ctr Micrograv Res Fluids & Combust, Cleveland, OH 44135 USA
来源
OPHTHALMIC TECHNOLOGIES XI | 2001年 / 4245卷
关键词
D O I
10.1117/12.429264
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Outer space is filled with high-energy ionizing radiation. Continuous radiation exposure or slight increase (e.g., due to flares) in it can be hazardous to astronaut health. Therefore cataractogenesis is a possible risk factor. In this paper we apply the sensitive technique of dynamic light scattering to investigate the simulated effects of X-ray exposure to the ocular tissue of non-human animals. An internet web based system integrates photon correlation data and controls the hardware for animal monitoring at a remote site in real time.
引用
收藏
页码:129 / 134
页数:6
相关论文
共 17 条
[1]  
Ansari R. R., 1998, JASMA J JAP SOC M S2, V15, P186
[2]   A fiber optic probe for monitoring protein aggregation, nucleation and crystallization [J].
Ansari, RR ;
Suh, KI ;
Arabshahi, A ;
Wilson, WW ;
Bray, TL ;
DeLucas, LJ .
JOURNAL OF CRYSTAL GROWTH, 1996, 168 (1-4) :216-226
[3]   In-vivo "cataractograms" using a compact backscatter dynamic light scattering (DLS) probe [J].
Ansari, RR ;
Suh, KI ;
Tumminia, SJ ;
Russell, P ;
Zigler, JS .
MEDICAL APPLICATIONS OF LASERS IN DERMATOLOGY, OPHTHALMOLOGY, DENTISTRY, AND ENDOSCOPY, PROCEEDINGS OF, 1997, 3192 :202-210
[4]  
ANSARI RR, 2000, P SPIE, V3908
[5]  
ANSARI RR, 1999, Patent No. 5973779
[6]  
ANSARI RR, 1999, J DIABETES TECHNOLOG, V1, P159
[7]  
CHU B, 1974, DYNAMIC LIGHT SCATTE
[8]  
Fedorenko B. S., 1995, Physics of Particles and Nuclei, V26, P573
[9]   THE EFFECT OF X-IRRADIATION ON CATION-TRANSPORT IN RABBIT LENS [J].
MATSUDA, H ;
GIBLIN, FJ ;
REDDY, VN .
EXPERIMENTAL EYE RESEARCH, 1981, 33 (03) :253-265
[10]   INVIVO OBSERVATION OF LENS PROTEIN DIFFUSIVITY IN NORMAL AND X-IRRADIATED RABBIT LENSES [J].
NISHIO, I ;
WEISS, JN ;
TANAKA, T ;
CLARK, JI ;
GIBLIN, FJ ;
REDDY, VN ;
BENEDEK, GB .
EXPERIMENTAL EYE RESEARCH, 1984, 39 (01) :61-68