Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses

被引：805

作者：

Sallusto, F

Lanzavecchia, A

Mackay, CR

机构：

[1] Basel Inst Immunol, CH-4005 Basel, Switzerland

[2] Millennium Biotherapeut Inc, Cambridge, MA 02139 USA

来源：

IMMUNOLOGY TODAY | 1998年 / 19卷 / 12期

关键词：

D O I：

10.1016/S0167-5699(98)01346-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

T-cell priming occurs in the lymphoid tissue via T cell-dendritic cell interaction. Conversely, delayed-type hypersensitivity or allergic reactions can occur in any tissue, following interaction of T helper 1 (Th1) or Th2 cells with effector leukocytes. Here, Federica Sallusto and colleagues review the role played by chemokines and chemokine receptors in positioning T cells for the immune response.

引用

页码：568 / 574

页数：7

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