A facile and sensitive immunoassay for the detection of alpha-fetoprotein using gold-coated magnetic nanoparticle clusters and dynamic light scattering

被引：38

作者：

Chun, Changho ^{[1
]}

Joo, Jinmyoung ^{[1
]}

Kwon, Donghoon ^{[1
]}

Kim, Chang Sup ^{[1
]}

Cha, Hyung Joon ^{[1
]}

Chung, Myung-Sub ^{[2
]}

Jeon, Sangmin ^{[1
]}

机构：

[1] Pohang Univ Sci & Technol POSTECH, Dept Chem Engn, Pohang, South Korea

[2] Chung Ang Univ, Dept Food Sci & Technol, Anseong, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 39期

关键词：

PARTICLES; PROBES; ASSAY;

D O I：

10.1039/c1cc14024h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile and sensitive immunoassay protocol for the detection of alpha-fetoprotein (AFP) was developed using gold-coated iron oxide magnetic nanoclusters and dynamic light scattering (DLS) methods. The increase in the average particle size due to AFP-mediated aggregation was measured using DLS, and the detection limit was better than 0.01 ng mL(-1).

引用

页码：11047 / 11049

页数：3

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