Dendritic cells can initiate protective immune responses against malaria

被引：35

作者：

Bruña-Romero, O ^{[1
]}

Rodriguez, A ^{[1
]}

机构：

[1] NYU, Sch Med, Dept Med & Mol Parasitol, New York, NY 10010 USA

来源：

INFECTION AND IMMUNITY | 2001年 / 69卷 / 08期

关键词：

D O I：

10.1128/IAI.69.8.5173-5176.2001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

An understanding of the antigen presentation mechanisms that mediate induction of protective immune responses against malaria is essential for the development of successful immunization approaches. Here we show that dendritic cells presenting Plasmodium yoelii sporozoite antigens are able to activate specific CD4(+) and CD8(+) T cells and initiate protective immune responses against malaria in mice.

引用

页码：5173 / 5176

页数：4

共 30 条

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