Marine Polysaccharides from Algae with Potential Biomedical Applications

被引:474
作者
de Jesus Raposo, Maria Filomena [1 ]
Bernardo de Morais, Alcina Maria [1 ]
Santos Costa de Morais, Rui Manuel [1 ]
机构
[1] Univ Catolica Portuguesa Porto, CBQF, Lab Associado, Escola Super Biotecnol, P-4202401 Porto, Portugal
关键词
polysaccharides; algae; bioactive; biomedical; pharmaceuticals; therapeutics; drug delivery; regenerative medicine; wound management; MOLECULAR-WEIGHT FUCOIDAN; HERPES-SIMPLEX-VIRUS; HEPARIN-COFACTOR II; CONTAINING SULFATED POLYSACCHARIDES; HUMAN-IMMUNODEFICIENCY-VIRUS; MICROALGA PORPHYRIDIUM SP; MACROPHAGE-STIMULATION ACTIVITY; CLADOSIPHON-OKAMURANUS TOKIDA; CELL-WALL POLYSACCHARIDES; ULVA-PERTUSA CHLOROPHYTA;
D O I
10.3390/md13052967
中图分类号
R914 [药物化学];
学科分类号
100705 [微生物与生化药学];
摘要
There is a current tendency towards bioactive natural products with applications in various industries, such as pharmaceutical, biomedical, cosmetics and food. This has put some emphasis in research on marine organisms, including macroalgae and microalgae, among others. Polysaccharides with marine origin constitute one type of these biochemical compounds that have already proved to have several important properties, such as anticoagulant and/or antithrombotic, immunomodulatory ability, antitumor and cancer preventive, antilipidaemic and hypoglycaemic, antibiotics and anti-inflammatory and antioxidant, making them promising bioactive products and biomaterials with a wide range of applications. Their properties are mainly due to their structure and physicochemical characteristics, which depend on the organism they are produced by. In the biomedical field, the polysaccharides from algae can be used in controlled drug delivery, wound management, and regenerative medicine. This review will focus on the biomedical applications of marine polysaccharides from algae.
引用
收藏
页码:2967 / 3028
页数:62
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