The assignment of the absolute configuration of 1,2-diols by low-temperature NMR of a single MPA derivative

被引：22

作者：

Freire, F

Seco, JM

Quiñoá, E

Riguera, R

机构：

[1] Univ Santiago, Fac Quim, Dept Quim Organ, E-15782 Santiago De Compostela, Spain

[2] Univ Santiago, Fac Quim, Dept Quim Organ, E-15782 Santiago De Compostela, Spain

[3] Univ Santiago, CSIC, Unidad RMN Biomol, E-15782 Santiago De Compostela, Spain

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 22期

关键词：

D O I：

10.1021/ol051764s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The absolute configuration of 1,2-primary/secondary diols can be easily assigned by low-temperature NMR of a bis-MPA ester derivative. The assignment requires the analysis of just the methylene protons, is not limited by the absence of signals from the R group of the diol, and requires a very small and recoverable sample.

引用

收藏

页码：4855 / 4858

页数：4

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