KF-Al2O3 is an efficient solid support reagent for the acetylation of amines, alcohols, and phenols.: Impeding effect of solvent on the reaction rate

被引：69

作者：

Yadav, VK ^{[1
]}

Babu, KG ^{[1
]}

Mittal, M ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India

来源：

TETRAHEDRON | 2001年 / 57卷 / 32期

关键词：

KF-Al2O3; acetylation; chemoselectivity; solvent effect;

D O I：

10.1016/S0040-4020(01)00677-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

KF-Al2O3 brings about rapid acetylation of a range of amines, alcohols, and phenols with Ac2O/AcCl. Aliphatic alcohols are acetylated chemoselectively in the presence of phenols. 1 degrees alcohols react several times faster than 2 degrees alcohols. 3 degrees alcohols do not react. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：7047 / 7051

页数：5

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