Heart Rate Variability in Children With Fontan Circulation: Lateral Tunnel and Extracardiac Conduit

被引:19
作者
Dahlqvist, Jenny Alenius [1 ]
Karlsson, Marcus [2 ]
Wiklund, Urban [2 ]
Hornsten, Rolf [3 ]
Stromvall-Larsson, Eva [7 ]
Berggren, Hakan [4 ]
Hanseus, Katarina [5 ]
Johansson, Sune [6 ]
Rydberg, Annika [1 ]
机构
[1] Umea Univ, Dept Clin Sci, S-90185 Umea, Sweden
[2] Umea Univ, Dept Biomed Engn & Informat, S-90185 Umea, Sweden
[3] Umea Univ, Dept Surg & Perioperat Sci, S-90185 Umea, Sweden
[4] Univ Gothenburg, Dept Cardiothorac Surg, Sahlgrenska Univ Hosp, Queen Silvia Childrens Hosp, S-41685 Gothenburg, Sweden
[5] Univ Lund Hosp, Dept Paediat, Childrens Hosp, S-22185 Lund, Sweden
[6] Univ Lund Hosp, Paediat Cardiac Surg Unit, Childrens Hosp, S-22185 Lund, Sweden
[7] Univ Gothenburg, Div Cardiol, Dept Paediat, Sahlgrenska Univ Hosp,Queen Silvia Childrens Hosp, S-41685 Gothenburg, Sweden
关键词
Extracardiac conduit; Fontan circulation; Heart rate variability; Lateral tunnel; TOTAL CAVOPULMONARY; ARRHYTHMIA; CONNECTIONS; ERA;
D O I
10.1007/s00246-011-0126-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The technique in Fontan surgery has developed from the lateral tunnel (LT) toward the extracardiac conduit (EC) used to reduce long-term complications such as atrial arrhythmia and sinus node dysfunction. Heart rate variability (HRV) examines cardiac nervous activity controlling the sinus node. This study aimed to investigate HRV in a cohort of children with univentricular hearts, focusing on the relation between HRV and surgical procedure. For 112 children with Fontan circulation, HRV was analyzed using power spectral analysis. Spectral power was determined in three regions: very-low-frequency (VLF), low-frequency (LF), and high-frequency (HF) regions. Patients were compared with 66 healthy controls subject. Patients with LT were compared with patients who had EC. The children with Fontan circulation showed a significantly reduced HRV including total power (P < 0.0001), VLF (P < 0.0001), LF (P < 0.0001), and HF (P = 0.001) compared with the control subjects. The LT and EC patients did not differ significantly. Reduced HRV was found in both the LT and EC patients. In terms of HRV reduction, EC was not superior to LT.
引用
收藏
页码:307 / 315
页数:9
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