Cell biology of the presynaptic terminal

被引:249
作者
Murthy, VN
De Camilli, P
机构
[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA
[2] Yale Univ, Sch Med, Dept Cell Biol, Howard Hughes Med Inst, New Haven, CT USA
关键词
synaptic vesicle; endocytosis; exocytosis; synaptic transmission; synaptic adhesion;
D O I
10.1146/annurev.neuro.26.041002.131445
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The chemical synapse is a specialized intercellular junction that operates nearly autonomously to allow rapid, specific, and local communication between neurons. Focusing our attention on the presynaptic terminal, we review the current understanding of how synaptic morphology is maintained and then the mechanisms in synaptic vesicle exocytosis and recycling.
引用
收藏
页码:701 / 728
页数:28
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