Histone octamer transfer by a chromatin-remodeling complex

被引:233
作者
Lorch, Y [1 ]
Zhang, M [1 ]
Kornberg, RD [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Biol Struct, Stanford, CA 94305 USA
关键词
D O I
10.1016/S0092-8674(00)80551-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
RSC, an abundant, essential chromatin-remodeling complex related to SWI/SNF complex, catalyzes the transfer of a histone octamer from a nucleosome core particle to naked DNA. The newly formed octamer-DNA complex is identical with a nucleosome in all respects. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. The mechanism may entail formation of a duplex displacement loop on the nucleosome, facilitating the entry of exogeneous DNA and the release of the endogenous molecule.
引用
收藏
页码:389 / 392
页数:4
相关论文
共 13 条
  • [1] Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF
    Cairns, BR
    Erdjument-Bromage, H
    Tempst, P
    Winston, F
    Kornberg, RD
    [J]. MOLECULAR CELL, 1998, 2 (05) : 639 - 651
  • [2] RSC, an essential, abundant chromatin-remodeling complex
    Cairns, BR
    Lorch, Y
    Li, Y
    Zhang, MC
    Lacomis, L
    ErdjumentBromage, H
    Tempst, P
    Du, J
    Laurent, B
    Kornberg, RD
    [J]. CELL, 1996, 87 (07) : 1249 - 1260
  • [3] STIMULATION OF GAL4 DERIVATIVE BINDING TO NUCLEOSOMAL DNA BY THE YEAST SWI/SNF COMPLEX
    COTE, J
    QUINN, J
    WORKMAN, JL
    PETERSON, CL
    [J]. SCIENCE, 1994, 265 (5168) : 53 - 60
  • [4] Perturbation of nucleosome core structure by the SWI/SNF complex persists after its detachment, enhancing subsequent transcription factor binding
    Côté, J
    Peterson, CL
    Workman, JL
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (09) : 4947 - 4952
  • [5] THE DROSOPHILA SNR1 AND BRM PROTEINS ARE RELATED TO YEAST SWI/SNF PROTEINS AND ARE COMPONENTS OF A LARGE PROTEIN COMPLEX
    DINGWALL, AK
    BEEK, SJ
    MCCALLUM, CM
    TAMKUN, JW
    KALPANA, GV
    GOFF, SP
    SCOTT, MP
    [J]. MOLECULAR BIOLOGY OF THE CELL, 1995, 6 (07) : 777 - 791
  • [6] FACILITATED BINDING OF TATA-BINDING PROTEIN TO NUCLEOSOMAL DNA
    IMBALZANO, AN
    KWON, H
    GREEN, MR
    KINGSTON, RE
    [J]. NATURE, 1994, 370 (6489) : 481 - 485
  • [7] KORNBERG RD, 1989, METHOD ENZYMOL, V170, P3
  • [8] NUCLEOSOMES INHIBIT THE INITIATION OF TRANSCRIPTION BUT ALLOW CHAIN ELONGATION WITH THE DISPLACEMENT OF HISTONES
    LORCH, Y
    LAPOINTE, JW
    KORNBERG, RD
    [J]. CELL, 1987, 49 (02) : 203 - 210
  • [9] Activated RSC-nucleosome complex and persistently altered form of the nucleosome
    Lorch, Y
    Cairns, BR
    Zhang, MC
    Kornberg, RD
    [J]. CELL, 1998, 94 (01) : 29 - 34
  • [10] Human SWI/SNF interconverts a nucleosome between its base state and a stable remodeled state
    Schnitzler, G
    Sif, S
    Kingston, RE
    [J]. CELL, 1998, 94 (01) : 17 - 27