Monoclonal antibodies to CD4

被引：20

作者：

Breedveld, FC ^{[1
]}

机构：

[1] Leiden Univ, Med Ctr, Dept Rheumatol, NL-2300 RC Leiden, Netherlands

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 1998年 / 24卷 / 03期

关键词：

D O I：

10.1016/S0889-857X(05)70026-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Animal models of human autoimmune disease suggest that it should be possible to reinduce self-tolerance in these conditions by the use of T-cell directed therapies, in particular with anti-CD4 monoclonal antibodies (CD4-mAb). Many studies have shown that CD4-mAb can prevent and in a treatment setting suppress activity of these disease models, including collagen-induced arthritis.

引用

页码：567 / +

页数：14