Beta-lactams derived from the reaction of phenanthridines and 11H-dibenzo[b,e]azepin-11-one with phenylvaleryl chloride.: Synthesis of fused analogs of the cholesterol absorption inhibitor Sch 48461.

被引：20

作者：

Afonso, A

Rosenblum, SB

Puar, MS

McPhail, AT

机构：

[1] Schering Plough Corp, Inst Res, Kenilworth, NJ 07033 USA

[2] Duke Univ, Paul M Gross Chem Lab, Durham, NC 27706 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 41期

关键词：

D O I：

10.1016/S0040-4039(98)01648-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Phenanthridines 4 and the 11H-dibenzo[b,e]azepin-11-one 17 were used as the imine components in the ketene-imine beta-lactam synthesis to provide the fused tetracyclic beta-lactams 7, 8 and 18. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：7431 / 7434

页数：4

共 8 条

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