TRANS DIASTEREOSELECTIVE SYNTHESIS OF 3-ALKYL SUBSTITUTED BETA-LACTAMS VIA THE ACID CHLORIDE-IMINE REACTION OF NONACTIVATED ACID-CHLORIDES

被引：59

作者：

BROWNE, M ^{[1
]}

BURNETT, DA ^{[1
]}

CAPLEN, MA ^{[1
]}

CHEN, LY ^{[1
]}

CLADER, JW ^{[1
]}

DOMALSKI, M ^{[1
]}

DUGAR, S ^{[1
]}

PUSHPAVANAM, P ^{[1
]}

SHER, R ^{[1
]}

VACCARO, W ^{[1
]}

VIZIANO, M ^{[1
]}

ZHAO, HR ^{[1
]}

机构：

[1] SCHERING PLOUGH CORP,RES INST,KENILWORTH,NJ 07033

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 15期

关键词：

D O I：

10.1016/0040-4039(95)00338-D

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New conditions for the acid chloride-imine reaction of nonactivated alkyl acid chlorides provide 3-alkyl substituted beta-lactams in good yields with high trans selectivity.

引用

页码：2555 / 2558

页数：4

共 14 条

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