Response to Xu et al:: Hypothesis-driven science paves the way for new discoveries

被引：3

作者：

Possani, LD ^{[1
]}

de la Vega, RCR ^{[1
]}

机构：

[1] Natl Autonomous Univ Mexico, Dept Mol Med & Bioproc, Inst Biotechnol, Cuernavaca 62210, Morelos, Mexico

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 2003年 / 24卷 / 09期

关键词：

D O I：

10.1016/S0165-6147(03)00224-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：448 / 449

页数：2

共 11 条

[1] A large number of novel Ergtoxin-like genes and ERG K+-channels blocking peptides from scorpions of the genus Centruroides [J].

Corona, M ;

Gurrola, GB ;

Merino, E ;

Cassulini, RR ;

Valdez-Cruza, NA ;

García, B ;

Ramírez-Domínguez, ME ;

Coronas, FIV ;

Zamudio, FZ ;

Wanke, E ;

Possani, LD .

FEBS LETTERS, 2002, 532 (1-2) :121-126

[2] Novel interactions between K+ channels and scorpion toxins [J].

de la Vega, RCR ;

Merino, E ;

Becerril, B ;

Possani, LD .

TRENDS IN PHARMACOLOGICAL SCIENCES, 2003, 24 (05) :222-227

[3] X-ray structure of a voltage-dependent K+ channel [J].

Jiang, YX ;

Lee, A ;

Chen, JY ;

Ruta, V ;

Cadene, M ;

Chait, BT ;

MacKinnon, R .

NATURE, 2003, 423 (6935) :33-41

[4] Database verification studies of SWISS-PROT and GenBank [J].

Karp, PD ;

Paley, S ;

Zhu, JC .

BIOINFORMATICS, 2001, 17 (06) :526-532

[5] Evolutionary predictions of binding surfaces and interactions [J].

Lichtarge, O ;

Sowa, ME .

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2002, 12 (01) :21-27

[6] Structural and functional role of the extracellular S5-P linker in the HERG potassium channel [J].

Liu, J ;

Zhang, M ;

Jiang, M ;

Tseng, GN .

JOURNAL OF GENERAL PHYSIOLOGY, 2002, 120 (05) :723-737

[7] Mapping the binding site of a human ether-a-go-go-related gene-specific peptide toxin (ErgTx) to the channel's outer vestibule [J].

Pardo-Lopez, L ;

Zhang, M ;

Liu, J ;

Jiang, M ;

Possani, LD ;

Tseng, GN .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (19) :16403-16411

[8] Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin [J].

Torres, AM ;

Bansal, P ;

Alewood, PF ;

Bursill, JA ;

Kuchel, PW ;

Vandenberg, JI .

FEBS LETTERS, 2003, 539 (1-3) :138-142

[9]

XU CQ, 2003, TRENDS PAHRM SCI, V24

[10] An accurate, sensitive, and scalable method to identify functional sites in protein structures [J].

Yao, H ;

Kristensen, DM ;

Mihalek, I ;

Sowa, ME ;

Shaw, C ;

Kimmel, M ;

Kavraki, L ;

Lichtarge, O .

JOURNAL OF MOLECULAR BIOLOGY, 2003, 326 (01) :255-261

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