Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

被引：1238

作者：

Zhang, Haibo ^{[1
,2
,3
,6
]}

Penninger, Josef M. ^{[4
,5
]}

Li, Yimin ^{[3
]}

Zhong, Nanshan ^{[3
]}

Slutsky, Arthur S. ^{[1
,2
,3
]}

机构：

[1] St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr Biomed Sci, 209 Victoria St,Room 608, Toronto, ON M5B 1T8, Canada

[2] Univ Toronto, Interdept Div Crit Care Med, Toronto, ON, Canada

[3] Guangzhou Med Univ, Affiliated Hosp 4, Guangzhou Inst Resp Hlth, State Key Lab Resp Dis, Guangzhou, Peoples R China

[4] Univ British Columbia, Dept Med Genet, Life Sci Inst, Vancouver, BC, Canada

[5] Austrian Acad Sci, IMBA, Inst Mol Biotechnol, Vienna, Austria

[6] Univ Toronto, Dept Anesthesia & Physiol, Toronto, ON, Canada

来源：

INTENSIVE CARE MEDICINE | 2020年 / 46卷 / 04期

基金：

加拿大健康研究院;

关键词：

SARS CORONAVIRUS; FUNCTIONAL RECEPTOR; PATHOGENESIS; PROTEIN;

D O I：

10.1007/s00134-020-05985-9

中图分类号：

R4 [临床医学];

学科分类号：

100218 [急诊医学];

摘要：

[No abstract available]

引用

页码：586 / 590

页数：5

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