Physiological effects of hyperchloraemia and acidosis

被引：118

作者：

Handy, J. M. ^{[1
]}

Soni, N. ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Chelsea & Westminster NHS Fdn Trust, London SW10 9NH, England

来源：

BRITISH JOURNAL OF ANAESTHESIA | 2008年 / 101卷 / 02期

关键词：

acid-base equilibrium; metabolic acidosis; complications; acidosis; fluids; i.v; ions; intracellular; metabolism; lactate;

D O I：

10.1093/bja/aen148

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

The advent of balanced solutions for i.v. fluid resuscitation and replacement is imminent and will affect any specialty involved in fluid management. Part of the background to their introduction has focused on the non-physiological nature of 'normal' saline solution and the developing science about the potential problems of hyperchloraemic acidosis. This review assesses the physiological significance of hyperchloraemic acidosis and of acidosis in general. It aims to differentiate the effects of the causes of acidosis from the physiological consequences of acidosis. It is intended to provide an assessment of the importance of hyperchloraemic acidosis and thereby the likely benefits of balanced solutions.

引用

页码：141 / 150

页数：10

共 113 条

[31] DISSOCIATION OF [H+] FROM FATIGUE IN HUMAN MUSCLE DETECTED BY HIGH TIME RESOLUTION P-31-NMR [J].