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Oxindole synthesis through intramolecular nucleophilic addition of vinylpalladiums to aryl isocyanates

被引：71
作者：
Kamijo, S
Sasaki, Y
Kanazawa, C
Schüsseler, T
Yamamoto, Y
机构：
[1] Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA
[2] Rhein Westfal TH Aachen, Inst Organ Chem, D-52074 Aachen, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 47期
关键词：
alkynes; isocyanates; nucleophilic addition; oxindoles; palladium;
D O I：
10.1002/anie.200502252
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Chemical Equation Presented) Ringing the changes for organopalladium catalysts. A new nucleophilic reactivity of organopalladium species has been revealed. The reaction between aryl isocyanates and terminal alkynes in the presence of a palladium catalyst produces oxindoles through the intramolecular vinylpalladation of isocyanates (see scheme; dppe = 1,2-bis(diphenylphosphanyl) ethane). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：7718 / 7721
页数：4
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