Quantitative MR temperature monitoring of high-intensity focused ultrasound therapy

被引：87

作者：

Bohris, C ^{[1
]}

Schreiber, WG ^{[1
]}

Jenne, J ^{[1
]}

Simiantonakis, I ^{[1
]}

Rastert, R ^{[1
]}

Zabel, HJ ^{[1
]}

Huber, P ^{[1
]}

Bader, R ^{[1
]}

Brix, G ^{[1
]}

机构：

[1] German Canc Res Ctr, Res Program Radiol Diagnost & Therapy, Dept Radiol, D-69120 Heidelberg, Germany

来源：

MAGNETIC RESONANCE IMAGING | 1999年 / 17卷 / 04期

关键词：

temperature mapping; image guided therapy; high intensity focused ultrasound; laser-induced thermotherapy;

D O I：

10.1016/S0730-725X(98)00196-9

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A new quantitative method has been developed for real-time mapping of temperature changes induced by high intensity focused ultrasound (HIFU), It is based on the temperature dependence of the T-1 relaxation time and the equilibrium magnetization, To calibrate the temperature measurement, the functional relationship between T-1 and temperature was examined in different samples of porcine muscle and fatty tissue. The method was validated by a comparison of calculated temperature maps with fiber-optic measurements in heated muscle tissue. The experiment showed that the accuracy of the MR method for temperature measurements is better than 1 degrees C, Since the acquisition time of the employed MR sequence Lakes only 3 s per slice and the calculation of the temperature map can be performed within seconds, the imaging technique works nearly in real-time. The temperature measurement could be realized during HIFU showing no disturbances by ultrasound sonication. In comparison to other MR approaches, the advantages of the introduced method lie in a sufficient accuracy and time resolution combined with a reasonable robustness against motion as well as the feasibility for temperature monitoring in fatty tissues. (C) 1999 Elsevier Science Inc.

引用

页码：603 / 610

页数：8

共 27 条

[1]

BOHRIS C, 1998, 6 M INT SOC MAGN RES, P2001

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