Suzuki coupling reactions of heteroarylboronic acids with aryl halides and arylboronic acids with heteroaryl bromides using a tetraphosphine/palladium catalyst

被引：60

作者：

Kondolff, I

Doucet, H

Santelli, M

机构：

[1] CNRS, UMR 6180, F-13397 Marseille, France

[2] Univ Aix Marseille 3, Fac Sci St Jerome, Synth Organ Lab, F-13397 Marseille, France

来源：

SYNLETT | 2005年 / 13期

关键词：

heteroaryl bromides; arylboronic acids; Suzuki reaction; heteroarylboronic acids;

D O I：

10.1055/s-2005-871951

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

cis,cis,cis-1,2,3,4-Tetrakis(diphenylphosphinomethyl)cyclopentane/[PdCl(C3H5)](2) efficiently catalyses the Suzuki reaction of heteroarylboronic acids with aryl bromides and also the coupling of arylboronic acids with heteroaryl bromides. The coupling of thiopheneboronic acids, 3-furanboronic acid and 3-pyridineboronic acid with a variety of aryl bromides gave the corresponding adducts in good yields. However, in most cases, better results in terms of substrate/catalyst ratio were obtained for the reaction of heteroaryl bromides with arylboronic acids.

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收藏

页码：2057 / 2061

页数：5

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