The Suzuki-Miyaura cross coupling reactions on solid support.: Link to solution phase directed ortho metalation.: The Leznoff acetal linker approach to biaryl and heterobiaryl aldehydes

被引：67

作者：

Chamoin, S

Houldsworth, S

Kruse, CG

Bakker, WI

Snieckus, V ^{[1
]}

机构：

[1] Univ Waterloo, Guelph Waterloo Ctr Grad Work Chem, Waterloo, ON N2L 3G1, Canada

[2] Solvay Duphar BV, Pharmaceut Res Labs, NL-1380 DA Weesp, Netherlands

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 24期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/S0040-4039(98)00779-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the titled compounds by Suzuki-Miyaura cross coupling on Merrifield resin - Leznoff acetal - linked halo benzaldehydes followed by mild acid hydrolysis is reported; synthetic utility for heterocycles based on solution phase Directed ortho Metalation chemistry is demonstrated. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：4179 / 4182

页数：4

共 8 条

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