Effect of alcohol on bacterial hemolysis

被引:6
作者
Shirron, Natali [3 ]
Korem, Moshe [3 ]
Shuster, Amir [3 ]
Leikin-Frenkel, Alicia [2 ]
Rosenberg, Mel [1 ,3 ]
机构
[1] Tel Aviv Univ, Dept Human Microbiol, Sackler Sch Med, Ramat Aviv, Israel
[2] Tel Aviv Univ, Minerva Ctr, Sackler Fac Med, Ramat Aviv, Israel
[3] Tel Aviv Univ, Sackler Sch Med, Dept Human Microbiol, IL-69978 Tel Aviv, Israel
关键词
D O I
10.1007/s00284-008-9196-7
中图分类号
Q93 [微生物学];
学科分类号
071005 [微生物学]; 100705 [微生物与生化药学];
摘要
Hemolysis of blood agar is broadly used as a diagnostic tool for identifying and studying pathogenic microorganisms. We have recently shown that alcohol vapors can confer hemolytic properties on otherwise nonhemolytic fungi (microbial alcohol-conferred hemolysis; MACH). Until now, this phenomenon has been found in various yeast strains and other fungi, but only in a few bacterial species (e.g., staphylococci). In the current study we (1) determined the extent of the above phenomenon in various Gram-positive and Gram-negative laboratory bacterial strains and in clinical bacterial isolates, (2) validated the observed hemolysis using a quantitative technique, and (3) provided evidence that the observed alcohol-mediated hemolysis may, at least in part, be related to synthesis of hemolytic lipids.
引用
收藏
页码:318 / 325
页数:8
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