A gold catalyst for carbene-transfer reactions from ethyl diazoacetate

被引：380

作者：

Fructos, MR

Belderrain, TR

de Frémont, P

Scott, NM

Nolan, SP ^{[1
]}

Díaz-Requejo, MM

Pérez, PJ

机构：

[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA

[2] Univ Huelva, Dept Quim & Ciencia Mat, Unidad Asociada, CSIC, Huelva 21007, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 33期

关键词：

C-H activation; carbenes; diazo compounds; gold; homogeneous catalysis;

D O I：

10.1002/anie.200501056

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Approaching El Dorado: A gold catalyst has been discovered that transfers a carbene unit from ethyl diazoacetate to aromatic substrates (see scheme) as well as olefins, amines, and alcohols. The insertion of carbene units into the C-H bonds of the aromatic ring of benzene, toluene, and styrene is a novel reaction. R = H, CH3, CH=CH 2; IPr = 1,3-bis(diisopropylphenyl)imidazol-2-ylidene. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：5284 / 5288

页数：5

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