Intermolecular copper-catalyzed carbon-hydrogen bond activation via carbene insertion

被引:119
作者
Díaz-Requejo, MM
Belderraín, TR
Nicasio, MC
Trofimenko, S
Pérez, PJ
机构
[1] Univ Huelva, Dept Quim & Ciencia Mat, Huelva 21819, Spain
[2] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA
关键词
D O I
10.1021/ja016798j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of catalysts of general formula TpXCu (TpX = homoscorpionate ligand) promote the insertion of :CHCO2Et (ethyl diazoacetate as the carbene source) into the C-H bonds of cycloalkanes and cyclic ethers in moderate to high yield. A correlation between the steric hindrance of these catalysts and the yield of the transformation has been observed. Copyright © 2002 American Chemical Society.
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页码:896 / 897
页数:2
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