Visible light-induced nuclease activity of a ternary mono-phenanthroline copper(II) complex containing L-methionine as a photosensitizer

被引：83

作者：

Patra, AK ^{[1
]}

Dhar, S ^{[1
]}

Nethaji, M ^{[1
]}

Chakravarty, AR ^{[1
]}

机构：

[1] Indian Inst Sci, Dept Inorgan & Phys Chem, Bangalore 560012, Karnataka, India

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 13期

关键词：

D O I：

10.1039/b303442a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ternary copper(II) complex, structurally characterized as [Cu(phen)(met)(MeOH)](ClO4) (1) by X-ray crystallography, has 1,10-phenanthroline (phen) as an intercalator/binder to supercoiled pUC19 DNA and L-methionine (met) as a photosensitizer, and the complex displays efficient photonuclease activity on irradiation with UV (312 nm) or visible (436, 532 nm) light through a mechanistic pathway involving singlet oxygen.

引用

页码：1562 / 1563

页数：2

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