Cloning, characterization, and expression analysis of hepcidin gene from red sea bream (Chrysophrys major)

被引：72

作者：

Chen, SL ^{[1
]}

Xu, MY ^{[1
]}

Ji, XS ^{[1
]}

Yu, GC ^{[1
]}

Liu, Y ^{[1
]}

机构：

[1] Chinese Acad Fisheries Sci, Yellow Sea Fisheries Res Inst, Qingdao 266071, Peoples R China

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 04期

关键词：

D O I：

10.1128/AAC.49.4.1608-1612.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A cDNA encoding hepcidin was isolated from a library of cDNA from spleen of red sea bream (Chrysophrys major) by expressed sequence tag analysis. The expression of the hepcidin mRNA in various tissues was examined. Challenge of red sea bream with Escherichia coli DH5 alpha elevated hepcidin mRNA levels in spleen, gill, liver, and intestine.

引用

页码：1608 / 1612

页数：5

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